- Kyle Freeland of the Colorado Rockies and Sandy Alcantara of the Miami Marlins will be the starting pitchers for the teams' Opening Day matchup.
- Freeland aims to build on his past performances, while Alcantara seeks to regain his dominant form after a challenging 2025 season.
- Both pitchers face challenges, with Freeland recovering from a back injury and Alcantara returning from Tommy John surgery, which could impact their starting performances and overall viability as the season progresses.